Genetic study of narcoleptic syndrome.
نویسندگان
چکیده
In this family study of the narcoleptic syndrome, 52% of the probands had an affected first degree relative, 41.9% of the sibs of those probands with an affected parent were similarly affected, 33.3% of the parents of 2 affected sibs and 41.2% of the children (after a correction for age) had narcolepsy, cataplexy, or both.
منابع مشابه
Executive attention and working memory in narcoleptic outpatients.
OBJECTIVE This pioneering study aimed to evaluate executive attention and working memory in Brazilian narcoleptic outpatients. METHODS Narcoleptic group: 19 treated narcoleptic outpatients (13 F; 6 M) (mean age=37.58; SD = 8.93); control group: 19 subjects (15 F; 4 M) (mean age=34.42; SD=12.31). INSTRUMENTS Epworth Sleepiness Scale - Brazilian Portuguese Version (ESS-BR), Victoria Stroop Te...
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Study carried out at Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil. Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil. Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada. Instituto Israelita de Ensino e Pesquisa do Hospital Israelita Albert Einstein, São Paulo (SP), Brazil. Financial support: AFIP & FAPESP � CEPID 98/14303-3. Confli...
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Neuroimaging techniques have refined the characterization of neural structures involved in the regulation of normal sleep-wake cycle in healthy humans. Yet brain imaging studies in patients with sleep disorders still remain scarce. In narcoleptic patients, structural and functional brain imaging studies have suggested the involvement of the hypothalamus in the pathophysiology of narcolepsy, pla...
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INTRODUCTION Sleep abnormalities, including narcolepsy and cataplexy, are a common feature of Prader-Willi syndrome. Long-term treatment with the central nervous system stimulant modafinil has not been reported. In this case report we present a longitudinal perspective of sleep abnormalities in a nine-year-old Caucasian girl with Prader-Willi syndrome from age two to age nine, and detail the re...
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ورودعنوان ژورنال:
- Journal of medical genetics
دوره 15 4 شماره
صفحات -
تاریخ انتشار 1978